Selected Papers 013113

biochemistry
Spontaneous Network Formation among Cooperative RNA Replicators
Cellular Crowding Imposes Global Constraints on the Chemistry and Evolution of Proteomes

calcium, ER & plasma membrane
Sub-resolution Lipid Domains Exist in the Plasma Membrane and Regulate Protein Diffusion and Distribution
ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology
Rab10 GTPase Regulates ER Dynamics and Morphology
Coordinated Oscillations in Cortical Actin and Ca2+ Correlate with Cycles of Vesicle Secretion
Calcium Oscillations-coupled Conversion of Actin Travelling Waves to Standing oscillations
Crystal Structure of the Calcium Release–Activated Calcium Channel Orai
Orai-STIM–mediated Ca2+ Release from Secretory Granules Revealed by a Targeted Ca2+ and pH Probe
Ca2+ Regulates T-cell Receptor Ativation by Modulating the Charge Property of Lipids
Single-molecule Analysis of Fluorescently Labeled G-protein–coupled Receptors Reveals Complexes with Distinct Dynamics and Organization
Mitochondrial Colocalization with Ca2+ Release Sites is Crucial to Cardiac Metabolism

cell polarity
Synthetic Spatially Graded Rac Activation Drives Cell Polarization and Movement
Modeling the Self-organized Phosphatidylinositol Lipid Signaling System in Chemotactic Cells Using Quantitative Image Analysis
Tracking Shallow Chemical Gradients by Actin-Driven Wandering of the Polarization Site
Non-uniform Membrane Diffusion Enables Steady-state Cell Polarization via Vesicular Trafficking

cell biology
Building Complexity: Insights into Self-Organized Assembly of Microtubule-Based Architectures [review]
The Problem of Colliding Networks and its Relation to Cell Fusion and Cancer
Predicting Rates of Cell State Change Caused by Stochastic Fluctuations Using a Data-driven Landscape Model
Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration
Guidance of Cell Migration by Substrate Dimension
An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
Tunable Signal Processing Through Modular Control of Transcription Factor Translocation

developmental biology
A Cell-Level Biomechanical Model of Drosophila Dorsal Closure

plant physiology, evolution
A Critical Transition in Leaf Evolution Facilitated the Cretaceous Angiosperm Revolution
Physical Limits to Leaf Size in Tall Trees

ecology
Different Types of Synchrony in Chaotic and Cyclic Communities
Recurrent Jellyfish Blooms Are a Consequence of Global Oscillations
The Ghost of Nestedness in Ecological Networks

evolution
Multiple Fitness Peaks on the Adaptive Landscape Drive Adaptive Radiation in the Wild
Predictability of Evolution Depends Nonmonotonically on Population Size

computational biology
Geometric Origin of Scaling in Large Traffic Networks

synthetic biology
Bottom-up Construction of in Vitro Switchable Memories
Towards a Bottom-up Reconstitution of Bacterial Cell Division [review]
Designing Biological Compartmentalization [review]
Directed Cytoskeleton Self-organization [review]
Directing the Assembly of Spatially Organized Multicomponent Tissues from the Bottom Up [review]
Design Principles of Regulatory Networks: Searching for the Molecular Algorithms of the Cell [review]

imaging
Optical Control of Protein Activity by Fluorescent Protein Domains
Ultrabright Photoactivatable Fluorophores Created by Reductive Caging